
EMBO Member
Romain Koszul
EMBO 2022
Former EMBO Young Investigator (2016)
Institut Pasteur, Paris, France
Functional organization of chromosomes
Our research is driven by long-standing interests in chromosome folding, dynamics and functional processes. We mainly focus on budding yeast, but also investigate species from all domains of life through complementary approaches, including large synthetic DNA molecules designed in silico. In parallel, we develop and apply computational techniques derived from the Hi-C technique, aiming at improving genome assembly and metagenomic analysis.
Keywords
Chromosome organization / yeast / genome stability & dynamics / genomics & computer biology / DNA repair / cohesin / synthetic chromosome