Institut Pasteur, Paris | France
Our research is driven by long-standing interests in chromosome folding, dynamics and functional processes. We mainly focus on budding yeast, but also investigate species from all domains of life through complementary approaches, including large synthetic DNA molecules designed in silico. In parallel, we develop and apply computational techniques derived from the Hi-C technique, aiming at improving genome assembly and metagenomic analysis.
Keywords: Chromosome organization / yeast / genome stability & dynamics / genomics & computer biology / DNA repair / cohesin / synthetic chromosome