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EMBO Member

Romain Koszul

Institut Pasteur, Paris | France

EMBO 2022

Functional organization of chromosomes

Our research is driven by long-standing interests in chromosome folding, dynamics and functional processes. We mainly focus on budding yeast, but also investigate species from all domains of life through complementary approaches, including large synthetic DNA molecules designed in silico. In parallel, we develop and apply computational techniques derived from the Hi-C technique, aiming at improving genome assembly and metagenomic analysis.

Keywords: Chromosome organization / yeast / genome stability & dynamics / genomics & computer biology / DNA repair / cohesin / synthetic chromosome

Subject area(s): Cell Cycle | Genome Stability & Dynamics | Genomic & Computational Biology | Microbiology, Virology & Pathogens | Systems Biology