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EMBO Associate Member

Ronald N. Germain

NIH, Bethesda | United States

EMBO 2008

Analysis of immunity using imaging and computation

My group studies basic aspects of innate and adaptive immune function, including biochemical mechanisms involved in antigen discrimination by T-cells, T-cell antigen-presenting cell interactions, and the subsequent delivery of effector function. We employ novel microscopic live animal and multiplex static imaging methods and computer modeling to create a detailed understanding of how the immune system operates in health and disease..

Keywords: Immunity / lymphocyte / antigen recognition / imaging / computer modeling

Subject area(s): Cell & Tissue Architecture | Immunology | Systems Biology