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EMBO Member

Rotem Sorek

Weizmann Institute of Science, Rehovot | Israel

EMBO 2018

The immune system of bacteria: CRISPR and beyond

Our lab of microbial genomics and systems biology focuses on deciphering the molecular mechanisms providing bacteria with protection against phages, known as the 'immune system' of bacteria. We study the CRISPR-Cas system, as well as new anti-phage defense systems we discovered. We also study how phages can communicate in order to coordinate their infection dynamics. An additional focus of the lab is RNA-mediated regulation in microbes.

Keywords: RNA / transcriptome / CRISPR-Cas / phage / bacterial communication

Subject area(s): Genomic & Computational Biology | Microbiology, Virology & Pathogens | Systems Biology