EMBO Associate Member
Ruth Lehmann
EMBO 2012
Whitehead Institute for Biomedical Research, Cambridge (MA), United States
Germ line biology
Our long-term goal is to functionally dissect the germ cell life cycle. We use Drosophila to study primordial germ cell (PGC) specification in the early embryo that makes them distinct from the mortal soma, the cellular mechanisms controlling PGC migration towards the somatic gonad, the regulatory network that allows germline stem cell maintenance in the adult and strategies that protect the germ cell genome from mobile elements and pathogens.
Keywords
Drosophila germ cells / cell migration & lipid biology / germ line stem cells / transposable element control / RNA biology