
Decoding the Notch Response
Much of our research is focused on an important pathway of cell communication, so-called Notch pathway. We aim to discover how signals through this pathway cause specific switches in gene activities to ensure the correct cell characteristics are made. This is important not only for understanding the normal process of development, but also for diseases, such as cancers, that arise through inappropriate Notch signals.
Keywords
Gene regulation / genomics / cell signalling / Drosophila / Notch