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EMBO Member

Sarah J. Butcher

University of Helsinki | Finland

EMBO 2018 | FelC 20–23

Macromolecular structure and assembly

Model systems or human adversary? We study virus structure, assembly and the underlying molecular mechanisms, aiming to understand how host-virus interactions occur and can be controlled, to fuel the design of new antiviral agents. We combine molecular biology with structural methods such as electron cryomicroscopy, X-ray crystallography and mass spectrometry to understand the importance of the spatial interactions that occur.

Keywords: Virology / cryo-EM / crystallography / virus-cell interactions

Subject area(s): Microbiology, Virology & Pathogens | Proteins & Biochemistry | Structural Biology & Biophysics