EMBO Member
Vilnius University, Vilnius | Lithuania
EMBO 2017
Besides our long standing interest in structural and mechanistic aspects of AdoMet-dependent enzymes, our efforts are now focussed on structure-based engineering of the DNA and RNA methyltransferase-catalyzed reactions and design of molecular tools for analysis of epigenetic regulation in mammalian organisms.
Keywords: DNA methylation / enzyme-cofactor engineering / epigenomic tools / methyltransferase mechanisms / chemo-enzymatic labeling of biopolymers
Subject area(s): Chromatin & Transcription | Genome Stability & Dynamics | Genomic & Computational Biology | Proteins & Biochemistry