
EMBO Associate Member
Scott D. Emr
EMBO 2008
Cornell University, Ithaca, United States
Endocytic trafficking and the and ESCRT complexes
Our research focuses on three topics: (1) the genetics of endocytic trafficking and receptor down-regulation; (2) genetic and biochemical analysis of phosphoinositide lipid- and ubiquitin-dependent membrane sorting and signaling pathways and (3) defining the pathways for maintaining the composition and quality of membrane proteins both at the plasma membrane and the lysosomal membrane (nutrient transporters, channels, receptors, etc.).
Keywords
Membrane trafficking / protein sorting / vesicles / phosphoinositide lipid signalling / multivesicular body