EMBO Member
Sean Munro
EMBO 1997 | Council 01–03 | Council 04–06 | WisC 14–18
MRC LMB, Cambridge, United Kingdom
The organisation of membrane traffic in the Golgi
The accuracy of membrane traffic depends on organelles having an 'identity' by which they can be recognised. This identity is defined by organelle-specific G proteins and phosphoinositide lipids. Focusing on the Golgi apparatus, we investigate how G proteins are activated in a spatially restricted manner, and identify the cytosolic proteins that then recognise them to direct accurate membrane traffic.
Keywords
Secretory pathway / Golgi apparatus / small G proteins / coiled-coil proteins