EMBO Member
Sebastian Amigorena
EMBO 2006
Institut Curie, Paris, France
Dendritic cells and antigen presentation
My main scientific interest overlaps immunology and cell biology. I am interested in antigen presentation and cross presentation in dendritic cells, and have described several unique specializations of their phagocytic pathway. We also made contributions to the analysis of cytotoxic T cells dynamics in vivo, during the initiation of immune responses in lymph nodes and during the invasion and rejection of solid tumors.
Keywords
Antigen presentation / dendritic cells / phagocytosis / tumor immunology / immunotherapy