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EMBO Member

Sebastian Amigorena

Institut Curie, Paris | France

EMBO 2006

Dendritic cells and antigen presentation

My main scientific interest overlaps immunology and cell biology. I am interested in antigen presentation and cross presentation in dendritic cells, and have described several unique specializations of their phagocytic pathway. We also made contributions to the analysis of cytotoxic T cells dynamics in vivo, during the initiation of immune responses in lymph nodes and during the invasion and rejection of solid tumors.

Keywords: Antigen presentation / dendritic cells / phagocytosis / tumor immunology / immunotherapy

Subject area(s): Immunology | Membranes & Transport | Signal Transduction