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EMBO Young Investigator

Sebastian Falk

Max Perutz Labs, Vienna | Austria

YIP 2023–2026

Biogenesis and action of small RNAs

Our group studies the role of small RNAs in regulating gene expression via the RNA interference pathway, specifically focusing on small RNA biogenesis pathways and the ability of small RNAs to induce transcriptional gene silencing in the nucleus. We employ a combination of biochemical reconstitution and structural biology approaches to gain mechanistic insights into these processes at the molecular level.

Keywords: Gene expression / sRNA / piRNA / RNA surveillance / structural biology

Subject area(s): Proteins & Biochemistry | RNA | Structural Biology & Biophysics