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EMBO Young Investigator

Sebastian Marquardt

University of Copenhagen, Frederiksberg | Denmark

YIP 2020–2024

Epigenetics of genomic punctuation

My group studies chromatin signaling linked to the act of RNA polymerase II transcription. We follow the hypothesis that co-transcriptional epigenetic signals provide an important model to interpret functions of non-coding DNA. In particular, we are investigating in yeast and plant systems how non-coding gene isoforms confuse chromatin-based genomic punctuation that underlies gene expression.

Keywords: Chromatin / transcription / non-coding RNA / epigenetics / environment / plant biology / biotechnology

Subject area(s): Chromatin & Transcription | Genome Stability & Dynamics | RNA