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EMBO Member

Simon Alberti

Technische Universit├Ąt, Dresden | Germany

EMBO 2023

Biomolecular condensates in stress and disease

My group uses biochemical, biophysical, cell biological and genetic approaches as well as diverse model systems to investigate the assembly and function of biomolecular condensates. The primary focus of the group is to understand how condensates protect cells from environmental perturbations and stress and how condensates become dysfunctional and cause age-related disease such as neurodegeneration and cancer.

Keywords: Stress adaptation / prion-like proteins / phase separation / biomolecular condensates / protein quality control

Subject area(s): Cellular Metabolism | Proteins & Biochemistry | Structural Biology & Biophysics