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EMBO Member

Simon Boulton

Francis Crick Institute, London | United Kingdom

EMBO 2009

Mechanisms of repair in mitotic and meiotic cells

The long-term goal of my lab is to understand how the DNA double-strand break (DSB) repair pathways of non-homologous end joining (NHEJ) and homologous recombination (HR) are regulated during the cell cycle, at replication forks, at telomeres and during meiosis. We also have an active interest in understanding how these pathways impact on human diseases such as cancer.

Keywords: DNA repair / recombination / checkpoints / genome stability

Subject area(s): Genome Stability & Dynamics