MRC LMB, Cambridge | United Kingdom
The primary goal of my group is to elucidate how microtubule-based cargo trafficking is controlled in time and space. We use a spectrum of techniques, from structural and single molecule approaches to visualisation of transport in a living organism. We have a long standing interest in how mRNAs are sorted to specific locations by molecular motors and have recently started to study this process in the intact nervous system of Drosophila.
Keywords: mRNA localisation / microtubule motors / cytoskeleton / Drosophila / CRISPR-Cas