
EMBO Member
Sophie G. Martin
EMBO 2020
Former EMBO Young Investigator (2010)
University, Geneva, Switzerland
Cell polarization and cell fusion
My lab aims to understand how spatial organization underlies cell physiology. Our work uses a simple eukaryotic model, the fission yeast Schizosaccharomyces pombe, to reveal conceptual principles and molecular details of cell polarization. Using advanced live-microscopy and molecular genetic techniques, we have made contributions to fields of cell growth control, cell division, signal transduction and sexual differentiation.
Keywords
Cell polarity / actin cytoskeleton / formin / Cdc42 GTPase / cell-cell fusion / membrane remodelling / sterol transfer / fission yeast Schizosaccharomyces pombe