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Organisation and dynamics of synaptic active zones

I seek to decipher how synapses, particularly their presynaptic active zones, assemble their protein architectures to support specific brain functions and behavioural adaptation. Thus, I adapt novel imaging techniques, particularly, super-resolution light microscopy (STED). I also analyse mechanisms of age-induced memory impairment, and thus could initiate the clinical testing of spermidine supplementation as an anti-brain-aging strategy.