Institut de Biologie Valrose, Nice | France
Our lab uses Drosophila as a model to study body patterning (left/right asymmetry) and organ morphogenesis during development (dorsal closure, oogenesis). In particular, we try to understand how the conserved Myosin ID and actin control L/R asymmetry in flies and zebrafish. We also study how specific organs acquire their shape and function through JNK signaling, cell reprogramming and the specific assembly and organization of the extracellular matrix.
Keywords: Drosophila / left-right asymmetry / morphogenesis / myosin / dorsal closure / oogenesis / patterning / JNK / extracellular matrix