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EMBO Member

Stephen P. Jackson

CRUK Cambridge Institute | United Kingdom

EMBO 1997

DNA damage detection, signalling and repair

The aim of my research is to better understand how cells detect DNA damage and signal its presence to the DNA repair and cell cycle machineries. Towards this end, my lab is using a broad range of techniques and approaches, in both mammalian and yeast cells. We believe this will lead to a better understanding of diseases such as cancer, neurodegeneration, and premature ageing – and will suggest new strategies for treating such diseases.

Keywords: DNA damage signalling / DNA repair / genetic recombination / cell cycle control / yeast molecular genetics

Subject area(s): Cell Cycle | Genome Stability & Dynamics | Molecular Medicine