DNA damage detection, signalling and repair
The aim of my research is to better understand how cells detect DNA damage and signal its presence to the DNA repair and cell cycle machineries. Towards this end, my lab is using a broad range of techniques and approaches, in both mammalian and yeast cells. We believe this will lead to a better understanding of diseases such as cancer, neurodegeneration, and premature ageing – and will suggest new strategies for treating such diseases.
Keywords
DNA damage signalling / DNA repair / genetic recombination / cell cycle control / yeast molecular genetics