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EMBO Associate Member

Susan Gottesman

NIH, Bethesda | United States

EMBO 2014

Post-transcriptional regulation in bacteria

Our lab is interested in post-transcriptional regulation in bacteria. We study regulated proteolysis by the ATP-dependent proteases, in particular the regulation of degradation of RpoS and the role of anti-adaptors in this process. We also study the physiological roles and mechanism of action of small non-coding RNAs, particularly those that utilize the RNA chaperone Hfq and regulated mRNA stability and translation.

Keywords: Small noncoding RNA / regulated proteolysis / iron metabolism / bacterial genetics / molecular microbiology

Subject area(s): Cellular Metabolism | Microbiology, Virology & Pathogens | Proteins & Biochemistry | RNA

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