
EMBO Member
Thomas Lecuit
EMBO 2009 | CouC 17–18
Former EMBO Young Investigator (2004)
Cell and tissue mechanics
We are interested in understanding the molecular mechanisms of tissue cohesion and plasticity. We focus our research on epithelial tissues, which form a robust barrier and are profoundly remodelled. Tissue growth and shape changes during morphogenesis require remodelling of cell contacts. We study how tissue level dynamics/cohesion emerges from the generation and transmission of adhesive and tensile forces at the cellular scale.
Keywords
Adhesion / cytoskeleton / mechanics / polarity / morphogenesis / Drosophila