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EMBO Member

Thomas Lecuit

Aix-Marseille Université, Marseille | France

EMBO 2009 | CouC 17–18

Cell and tissue mechanics

We are interested in understanding the molecular mechanisms of tissue cohesion and plasticity. We focus our research on epithelial tissues, which form a robust barrier and are profoundly remodelled. Tissue growth and shape changes during morphogenesis require remodelling of cell contacts. We study how tissue level dynamics/cohesion emerges from the generation and transmission of adhesive and tensile forces at the cellular scale.

Keywords: Adhesion / cytoskeleton / mechanics / polarity / morphogenesis / Drosophila

Subject area(s): Cell & Tissue Architecture | Development | Systems Biology