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EMBO Member

Tibor Harkany

Medical University of Vienna, Vienna | Austria

EMBO 2025

Developmental principles of drug abuse

Our work addresses the developmental design of neuroendocrine centers in the mammalian hypothalamus, with a focus on brain-wide and hierarchical connectivity and neuropeptide signals. Through a translational approach, we ask how the maternal abuse of illicit/prescription drugs during pregnancy can impose lifelong modifications to neuronal circuits and neuroendocrine modules, which then manifest as metabolic diseases in affected offspring.

Keywords: Brain / neuron / neuropeptide / cannabis / RNAseq / hypothalamus / development / endocrine disorders

Subject area(s): Cell & Tissue Architecture | Molecular Medicine | Neuroscience

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