EMBO Young Investigator
Tineke Lenstra
YIP 2023–2026
Netherlands Cancer Institute, Amsterdam, Netherlands
Transcription dynamics in single cells
Our lab aims to understand the molecular mechanisms and dynamics of eukaryotic transcription regulation. To study this, we use and develop cutting-edge single-molecule microscopy techniques to directly observe the stochastic behavior of regulatory factors and the process of transcription, as they dynamically occur inside living cells.
Keywords
Transcriptional bursting / single-molecule imaging / chromatin / transcriptional regulators / stochastic gene expression