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EMBO Young Investigator

Tineke Lenstra

Netherlands Cancer Institute, Amsterdam | Netherlands

YIP 2023–2026

Transcription dynamics in single cells

Our lab aims to understand the molecular mechanisms and dynamics of eukaryotic transcription regulation. To study this, we use and develop cutting-edge single-molecule microscopy techniques to directly observe the stochastic behavior of regulatory factors and the process of transcription, as they dynamically occur inside living cells.

Keywords: Transcriptional bursting / single-molecule imaging / chromatin / transcriptional regulators / stochastic gene expression

Subject area(s): Chromatin & Transcription | Structural Biology & Biophysics