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EMBO Member

Titia K. Sixma

Netherlands Cancer Institute, Amsterdam | Netherlands

EMBO 2004 | YipC 07–08 | Council 16–18 | Council 17–18

Structural biology of ubiquitin and DNA regulation

My group uses a combination of structural biology and quantitative biochemistry to provide insight in biological pathways focusing on two topics: a) regulation of ubiquitin conjugation and deconjugation b) initiation of DNA mismatch repair.

Keywords: DNA repair / ubiquitin conjugation / protein crystallography / ion channels

Subject area(s): Chromatin & Transcription | Genome Stability & Dynamics | Structural Biology & Biophysics