EMBO Member
Tom A. Rapoport
EMBO 1993
Harvard Medical School, Boston, United States
Protein translocation and membrane morphology
My lab is interested in 1. the mechanism by which proteins are transported across or inserted into the endoplasmic reticulum membrane in eukaryotes and the cytoplasmic membrane in bacteria; 2. the mechanism by which misfolded ER proteins are transported back into the cytosol for degradation (ERAD); 3. the mechanism by which the endoplasmic reticulum adopts its characteristic shape; 4. the mechanism by which proteins are imported into peroxisomes
Keywords
Intracellular protein transport / membrane curvature / ERAD / ER morphology / peroxisomal protein import