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EMBO Young Investigator

Uri Ben-David

University, Tel Aviv | Israel

YIP 2022–2025

Understanding and targeting cancer aneuploidy

Aneuploidy, a deviation from the normal chromosome number, is a fundamental, understudied trait of cancer. My lab develops and applies genomic and functional approaches to study the biological processes that lead to aneuploidy, uncover the selection pressures that shape aneuploidy evolution during tumor formation and progression, and design strategies to selectively target aneuploid cancer cells.

Keywords: Cancer genetics / aneuploidy / genome (in)stability / chromosome instability / tumor evolution

Subject area(s): Genome Stability & Dynamics | Genomic & Computational Biology | Molecular Medicine