EMBO Associate Member
Seoul National University | Korea, Republic of
Our lab studies RNA-mediated gene regulation in cell fate determination. We employ biochemistry, molecular biology, as well as genetic, biophysical, and computational approaches to investigate noncoding RNAs including microRNAs. Our contributions to the field include delineation of the microRNA biogenesis pathway and identification of several key factors such as Drosha. We have also been investigating the function and regulation of miRNAs in cancer and stem cells.
Keywords: microRNA / RNA processing / RNA interference / RNA silencing / stem cell