
Stat3 roles in tumorigenesis & inflammation/auto-immunity
Valeria Poli is full Professor in Molecular Biology at the University of Turin. She is interested in the signalling and transcriptional regulation by cytokines and growth factors both in vivo and in vitro. Her research mainly focuses on the core mechanisms through which the transcription factor Stat3 exerts its diverse functions at the crossroads between inflammation, immune response, auto-immunity, tumor and stem cell niche and tumor metabolism.
Keywords
Signalling / STAT transcription factors / inflammation / auto-immunity / energy metabolism / apoptosis / senescence / breast cancer