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EMBO Member

Valérie Borde

Institut Curie, Paris | France

EMBO 2024

Yeast meiotic and somatic homologous recombination

My lab studies how cells repair the double-strand breaks deliberately induced during meiosis, by homologous recombination. This step is essential for the accurate segregation of homologous chromosomes, and therefore for obtaining gametes (eggs or sperm) with a normal chromosome content, preventing aneuploidy at the source of chromosomal diseases or infertility.

Keywords: Meiosis / DNA double-strand break repair / homologous recombination / chromosome structure / chromatin / genomic studies

Subject area(s): Genome Stability & Dynamics | Chromatin & Transcription | Cell Cycle

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