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EMBO Member

Virginie Hamel

University, Geneva | Switzerland

EMBO 2026

Centriole and cilia assembly mechanisms

My group, which I co-lead with Paul Guichard, focuses on deciphering the structural and molecular mechanisms governing centriole and cilia assembly. We combine cell biology, expansion microscopy, in vitro reconstitution assays, and cryo-microscopy approaches to understand how these essential cellular structures are built and maintained, and how their dysfunction contributes to human disease.

Keywords: Centriole / cilia / microtubule / cryo-tomography / super-resolution microscopy / expansion microscopy / ciliopathies / organelles

Subject area(s): Cell Cycle | Cell & Tissue Architecture | Structural Biology & Biophysics

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