EMBO Global Investigator
Wee-Wei Tee
GIN 2022–2025
Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore
Chromatin control of cellular plasticity
My lab has a long-standing interest in understanding the epigenetic mechanisms of lineage plasticity in early development. More recently, we have broadened our investigations to study how cancer cells undergo epigenetic reprogramming to induce phenotypic plasticity. This cross-fertilisation strategy has been rewarding, directing us to uncover conserved mechanisms implicated in epigenetic reprogramming and exposing novel cancer vulnerabilities.
Keywords
Chromatin / reprogramming / stem cells / cancer