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EMBO Member

Wendy S. Barclay

Imperial College, London | United Kingdom

EMBO 2024

Respiratory viruses with pandemic potential

My research addresses how viruses of animals adapt to cause human pandemics. My lab's most significant discovery is the identity of a host factor, ANP32, co-opted by influenza virus to support RNA replication. During the COVID-19 pandemic, we pivoted to study SARS-CoV-2 and its variants. We employ molecular virology and in vivo approaches including human challenge to understand airborne transmission.

Keywords: Respiratory viruses / influenza / SARS-CoV-2 / ANP32 / RNA polymerase / pandemic / virus transmission

Subject area(s): Molecular Medicine | Microbiology, Virology & Pathogens