EMBO Member
Netherlands Cancer Institute, Amsterdam | Netherlands
EMBO 1991
The major focus of our research is on bioactive lysophospholipids, particularly the lipid growth factor LPA, its cognate receptors, signaling mechanisms and role in health and disease. In addition, we are studying how and where LPA is produced by autotaxin, a secreted phosphodiesterase implicated in tumor progression.
Keywords: Lipid mediators / growth factors / receptors / cell-cell communication
Subject area(s): Membranes & Transport | Molecular Medicine | Signal Transduction