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EMBO Member

Wouter H. Moolenaar

Netherlands Cancer Institute, Amsterdam | Netherlands

EMBO 1991

Lipid growth factor signaling

The major focus of our research is on bioactive lysophospholipids, particularly the lipid growth factor LPA, its cognate receptors, signaling mechanisms and role in health and disease. In addition, we are studying how and where LPA is produced by autotaxin, a secreted phosphodiesterase implicated in tumor progression.

Keywords: Lipid mediators / growth factors / receptors / cell-cell communication

Subject area(s): Membranes & Transport | Molecular Medicine | Signal Transduction