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EMBO Member

Xiaodong Zhang

Imperial College, London | United Kingdom

EMBO 2016

Structures and mechanisms of macromolecular machines

My research program focuses on unravelling the mechanisms of macromolecular machines using a range of structural biology techniques including X-ray crystallography and electron cryo-microscopy. My group is particularly interested in large macromolecular assemblies involved in DNA processing such as DNA damage response and repair, transcription regulation, as well as the structures and mechanisms of multi-functional AAA ATPase p97.

Keywords: Structural biology / transcription / DNA damage signalling and repair / AAA proteins / p97

Subject area(s): Chromatin & Transcription | Proteins & Biochemistry | Structural Biology & Biophysics