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EMBO Associate Member

Xiaowei Zhuang

Harvard University, Cambridge | United States

EMBO 2016

Advanced imaging of cellular structures

My lab develops imaging techniques with single-molecule sensitivity, molecular-scale resolution and genome-scale capacity to study problems of biomedical interest. For example, we invented a super-resolution imaging method, STochastic Optical Reconstruction Microscopy (STORM) and a transcriptome imaging method, multiplexed, error-robust fluorescence in situ hybridization (MERFISH). We apply these methods to investigating problems in the areas of cell biology and neurobiology.

Keywords: Super resolution imaging / single molecule analysis / FRET / neuron / cytoskeleton / chromatin / RNA / transcriptome

Subject area(s): Chromatin & Transcription | Neuroscience | Structural Biology & Biophysics