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EMBO Young Investigator

Yogesh Kulathu

University, Dundee | United Kingdom

YIP 2016

Ubiquitin signalling mechanisms

The research goal of my lab is to understand how ubiquitin signals are decoded and regulated to produce distinct cellular outcomes. We use a range of techniques, from structural and biochemical methods to genetic approaches in model organisms, to dissect ubiquitin signaling mechanisms in health and disease. We are particularly interested in addressing how T-lymphocyte activation and adaptive immune responses are modulated by the ubiquitin system.

Keywords: Ubiquitin / T lymphocytes / deubiquitinase / structural biology / protein degradation

Subject area(s): Immunology | Proteins & Biochemistry | Signal Transduction