EMBO Associate Member

Yoshinori Ohsumi

Tokyo Institute of Technology, Yokohama | Japan

EMBO 2013

Molecular mechanisms and roles of autophagy

My group has been working on the molecular mechanism and physiological functions of autophagy in yeast. We identified ATG genes essential for starvation-induced autophagy, and discovered protein kinase, PI3 kinase complex, and two ubiquitin- like conjugation systems. We are making efforts to elucidate the molecular details of membrane dynamics during autophagy.

Keywords: Protein degradation / autophagy / membrane biogenesis / yeast / vacuole

Subject area(s): Cellular Metabolism | Membranes & Transport | Proteins & Biochemistry