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EMBO Associate Member

Yukiko Goda

Institute of Science and Technology Graduate University, Okinawa | Japan

EMBO 2023

Tripartite synapse regulation in local circuits

We study how the dynamic features of synaptic connections mediate effective information processing in the brain. This involves not only the pre- and the postsynaptic sides of a synapse but also nearby synapses sharing the local circuit and the astrocyte network. We seek to understand the synaptic circuit architecture underlying learning and memory and its homeostatic maintenance against physiological changes and pathological insults.

Keywords: Synaptic strength / synaptic plasticity / synapse adhesion proteins / homeostatic plasticity / astrocyte / synaptic vesicle dynamics / local synaptic circuit

Subject area(s): Cell & Tissue Architecture | Membranes & Transport | Neuroscience | Signal Transduction