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Portrait of Zachary F. Mainen

EMBO Member

Zachary F. Mainen

EMBO 2010

Champalimaud Centre for the Unknown, Lisbon, Portugal

Systems and computational neuroscience

We are interested in understanding the principles underlying complex adaptive behavior. We integrate fine observations of animal behavior with quantitative, cellular and systems level analysis of underlying neural mechanisms with a theoretical context. Rodents provide flexible models that allow us to monitor and manipulate neural circuits using multiple techniques. Current foci include the serotonin system and decision-making under uncertainty.

Neurophysiology / optogenetics / decision-making / uncertainty / computational models / behavior