EMBO Member
Zoi Lygerou
EMBO 2014 | CouC 15–19 | CouC 20–22 | EEsC 20–21 | Council 24–26
Former EMBO Young Investigator (2002)
University, Patras, Greece
Control over DNA replication in eukaryotic cells
My group studies the control mechanisms which safeguard genomic stability by ensuring once-per-cell-cycle replication in eukaryotic cells, and how defects in this control may lead to tumorigenesis. We combine functional imaging in human cells, genetic studies in fission yeast and modelling to understand how chromatin-associated multi-protein complexes regulate DNA replication and repair in time and space.
Keywords
Cell cycle / DNA replication / genome stability / cell fate / chromatin / functional imaging / modeling / cancer