EMBO Member
Zoltán Ivics
EMBO 2026
Fraunhofer Institue for Cell Therapy and Immunology, Leipzig, Germany
Clinical translation of Sleeping Beauty
Our group focuses on the development of transposons as versatile, non-viral tools for genome engineering. Sleeping Beauty is one of the most outstanding examples for the potential of synthetic biology and represents a key enabling technology for gene transfer in vertebrate cells. We develop advanced reagents to improve both efficacy and safety of the system and clinically translate this technology for genetic medicines.
Keywords
Genome evolution / transposable elements / gene therapy / nonviral gene delivery / resurrected genes